I am not much for chains. If I would choose a chain to eat at it would be more fast food - Panera, Brueggers or Taco Johns
We have fantastic independent restaurants & bistros here that I love:
Lucca
Sage
Azalea's
Bistro Montage
Cafe Di Scala
Splash Seafood Bar & Grill
Waterfront Seafood Market
Mosaix
El Azteca Mexican Restaurant
Gateway Market
If you're ever in Des Moines - let's grab a bite to eat together