My Heidi was bitten by a large Rotty a couple of years ago, it was young and playful and being curious, it started playfully biting at her but it was too much for an elderley 6lb yorkie with paper thin skin and before i could lift her out of harms way he had punctured the skin on her back and she had to have a couple of staples put in. The picture below shows you what damage a FRIENDLY & PLAYFUL large dog can do to a small breed! you have to be constantly alert at all times while out with your little ones, My Pixie is coming up to 6 months old and weighs no more than about 2 pounds, if i see another dog coming whatever breed or size i pick her up, i just do not take any risks. I lost my beautiful Heidi in may this year aged 14.
 
   
Kez & Pixie x