My puppies are 7 weeks old and I am teaching them not to bite. The more your breeder does with them early on the better for you. Mine are held and snuggled constantly. I make sure they all feel relaxed while laying on their backs in my hands not held against me. Mine can be playing like crazy and I can pick them up and do this and they are ready for snuggle time. (I'm not bragging, just proud). They really are crazy little dogs at 10 weeks, they just don't think there is enough time in a day to let all of that energy burst out of them. I teach mine to "settle" when being held. Your pup should not squirm when you hold her. So try petting her while you are holding her to get her more used to it. Don't hold it against her or think she won't be a lap dog when she grows up (which is the key word here), she is behaving as a wild, crazy Yorkie puppy. You do have to let her know who is boss (and you'll be a lot better off if it is you!)