I have a 10 pound Maltese, and I give him 1/2 teaspoon children's liquid Benadryl. So I would think for a 4 pound dog, it would be about 1/4 teaspoon. I find the liquid is easier to give using a dropper...just squirt it in their mouth! Good luck!
__________________ ocmommyof2  Love my Delilah  , Joey  , and Madison |