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  In my opinion from the limited research I have done, I would never give a yorkie the lepto vaccine. The risk does not outweigh the benefits when I do the analysis. If you research it on the internet there are a lot of vets who disagree with most vaccinations including rabies and feel that this over vaccination is actually harmful to their health. Everyone has to do what is confortable for them, but I would certainly do all the research you can before scheduling the appointment and here at YT is a good start, but the internet has lots of good articles on the controversy.
 I would not allow more than one vaccine at a time either. It means more trips to the vet but it is what is in the dog's best interest.
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