Well, if she had been listless to date and is now chewing on a bone, that's a pretty good sign. It will take time though. Those meds are tough and once they really start to work, don't be surprised if she seems like she has gotten worse.
If this happens, it shouldn't go beyond a day if it's normal. Ears are even more vital to dogs than to us and probably a lot more sensitive, too.
Hang in there!
