I beleive Revolution has the heartworm medicine included...correct me if I am wrong..and frontline and advantage are similar..I THINK...I personally use FRONTLINE PLUS..and Interceptor for the heartworm pill... I apply the frontline and give the pill on the first of the month..every month..except I will not be gdoing the frontline during the winter because Maximus won't be outside....I only use the frontline because it is what my vet told me to use..but as far as that and advantage I think they are almsot the same |