I don't use bio spot...I heard it bad and burns the dogs skin.
I use Advantage.
Never had a problem with fleas.
The Trick is to buy the large weight size there is and
Have your Vet to tell you the correct amount to use on each dog.
Which is only a few drpps.
A syringe tube works great for correct amounts.
A big thing of it will run all my dog all year long and I have (7).
I Love Those Saving.....