I've been breaking out because I'm pregnant...anything you're not sharing
Just kidding, I used proactiv and it worked for awhile and then actually caused my face to break out again because it became too drying. (I can only use it for like 4 months at a time). I used to take oral antibiotics when I was a teen and they worked great...but dermatologists don't like you to be on those for too long, eventually they'll stop working as effectively. I would say if over the counters don't work, hit up a dermatologist for the most complete list of options that will work best for your skin.