As much as I love my yorkies, I am so against taking them on vacations, other than for a few days.
IMO, it's impossible to enjoy your vacation when you have to worry about a dog (or in my case, TWO!). I took them on a 4 night vacation in the fall and the entire time I was afraid of leaving them alone and someone (cleaning people, esp) coming in and little them. I couldn't even enjoy going out to dinner because I was afraid something would happen or they would start barking.
I say leave her at home, and enjoy your vacation.