I think it depends on your individual pet. Some pets react well to the vaccs and others do not. I no longer vaccinate my ferrets for instance because of their horrible reactions. All my dogs and cats do very well and therefore I do vaccinate them annually. I am a believer in administering vaccs in appropriate amounts but remember that a vacc only helps to protect from getting a disease not necessarily prevent it. All my dogs are up to date on all shots including bordetella kennel cough and yet all 6 developed kennel cough. So there is no 100% prevention but
to me the pros out weigh the cons. And in the end it's all about that, your opinion.
Do a lot of research and talk to A LOT of different vets, new science, old science and homeopathic vets. Get a feel for all the info so you can take it all in and then you can decide what's best for your pet. But remember, in most states (if not all.. not sure) rabies is a must by law.