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08-15-2006, 04:54 AM | #1 |
BANNED! Join Date: Mar 2005
Posts: 1,139
| Protein losing enteropathy I have never seen this mentioned on here and thought it would be good to post info on this disease that can affect yorkies. Disease Name Protein losing enteropathy Organ System Involved Gastrointestinal Alternative disorders described within LIDA Intestinal malabsorption Alternative Names Intestinal malabsorption Malabsorption syndrome Brief Description There is a certain level of protein normally present in the fraction of blood called 'plasma'. In protein losing enteropathy (PLE) this plasma protein is lost via the gastrointestinal tract. Presenting Signs Protein losing enteropathy is due to loss of blood plasma protein through the gastrointestinal tract (intestines). This can happen if the gut wall is damaged and protein-rich fluid leaks from the blood vessels into the intestine. It can also happen if lymphatic drainage is poor (the lymphatic system is a series of vessels that drain fluid). Clinically, it can be detected in a number of ways. One of the most common signs of PLE is long-term watery diarrhoea. Other signs, such as vomiting and severe weight loss, are also seen in some affected dogs. Also, dogs with this disease have excess fluid under the skin, in the abdomen and in the chest cavity around the lungs. In some cases, various skin problems such as allergy and skin and ear infections are present. Dogs at Risk Most common in younger dogs, especially females. Treatment Medical Related Disorders Food hypersensitivity Hypocholesterdemia Inflammatory bowel disease Lipogranulomatous lymphangitis Lymphgiectasia Panhypoproteinemia Protein losing nephropathy Thromboembolic |
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08-15-2006, 05:05 AM | #2 |
Yorkie Kisses are the Best! Donating Member | THANK YOU FOR POSTING THIS !! I hadn't seen it either - but in light of poor Sammi and all the Liver Shunt we see here - this is very very good information !! |
08-15-2006, 05:17 AM | #3 |
Donating YT 1000 Club Member Join Date: Jan 2006 Location: In my house :)
Posts: 5,219
| Do you have any information on the treatment of this disease? |
08-15-2006, 07:22 AM | #4 |
BANNED! Join Date: Mar 2005
Posts: 1,139
| http://avmajournals.avma.org/doi/abs...a.2000.217.703 http://www.marvistavet.com/html/body...giectasia.html This is the best I could do. |
08-15-2006, 07:38 AM | #5 |
Donating YT 1000 Club Member Join Date: Jan 2006 Location: Abbotsford, BC
Posts: 2,060
| Excellent information. I have heard of it although have not experienced it. |
08-15-2006, 08:01 AM | #6 |
BANNED! Join Date: Mar 2005
Posts: 1,139
| Lorraine perhaps you know.. How common is this problem? |
08-15-2006, 08:16 AM | #7 | |
Donating YT 1000 Club Member Join Date: Jan 2006 Location: Abbotsford, BC
Posts: 2,060
| Quote:
The ones I heard about did not survive. I will be talking to my Vet on Friday and he is very interested in all these things in various breeds so he could likely give me an idea how prevalent it would be in YOrkies or what breeds it may be showing up moreso. The other issue of course, is that really it has been maybe the last five years or so that much of this has been diagnosed or able to be diagnosed with the use of diagnostic equipment that is pretty accessible to the world of Veterinary medicine. That's why you are able to know so much more about Liver shunts, other liver disease issues either genetic or congenital, heart conditions, gastrointestinal issues such as this one, and the myriad of issues that can affect our companion animals. It has not been that many years either that OFA has been around for xraying hips and elbows on breeds that have hip displasia issues such as labs and Golden Retrievers. The Veterinarians that certifiy OFA have to be specially trained for it. A lot of these diseases hava been around for years but it would not have been known what happened when a dog or puppy died from something like liver shunt for example. | |
08-15-2006, 08:28 AM | #8 |
Always In My Heart Donating Member Join Date: Aug 2005 Location: The Lone Star State
Posts: 3,393
| wow... you know all of those signs u siad my madda had them.... I sometimes wonder if it really was parvo... I guessI am just second guessing myself, but truly those signs were alot similiar.. |
08-15-2006, 08:36 AM | #9 | |
Donating YT 1000 Club Member Join Date: Jan 2006 Location: Abbotsford, BC
Posts: 2,060
| Quote:
This is what I mean that some can die from this stuff but have been misdiagnosed as something else. I can't see a dog dying of Parvo that had their vaccinations done. If there was a vaccine problem there are always many affected not just one dog. | |
08-15-2006, 08:47 AM | #10 |
Donating YT 1000 Club Member Join Date: Jan 2006 Location: In my house :)
Posts: 5,219
| I'm wondering about this now...this is exactly what Boog went through when he was sick, he lost protien through the GI tract, had lots of fluid in his abdomen that had to be drained off or he had to take Lasix ro remove it and he had several plasma transfusions over the last couple years he was here. No matter what they did he would be well for a couple months and then he would get sick again. The vet thought he had Lymphangiectasia (sp?) but they were never really positive that's what it was...he was also tested for Cushing's and, I forgot the name, but it's the opposite of Cushing's along with so many other things...it seems like the tests were endless. This started with him in '01 or '02 and we lost him in '04...he was 12 years young and still acted like a puppy until this hit him. |
08-15-2006, 08:58 AM | #11 | |
Donating YT 1000 Club Member Join Date: Jan 2006 Location: Abbotsford, BC
Posts: 2,060
| Quote:
Cushings is harder to treat as there is too much steroid ( I believe if I recall correctly) being produced by the body. Cushings can occur in older dogs. Addison's, when it occurs, is more common in females usually between about 4 and 5 years old. I am not sure if protein losing enteropathy can occur at any age or is more risk to show up in younger, older or any age dogs. As I recall the cases I heard of were under a year of age but I don't know if it can occur in older dogs as well. | |
08-15-2006, 09:10 AM | #12 |
Donating YT 1000 Club Member Join Date: Jan 2006 Location: In my house :)
Posts: 5,219
| Yes, Addison's was the other one...he was negative for both of them and everything else they tested for...Boog was 8 or 9 when all of this started but he did have digestive issues (along with many other health issues) all of his life. |
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