It's all about how careful you want to be. Blood work is pretty important to check organ function, blood count, etc. You catch things before they present a big problem this way... They are extremely important after about age 5, but are a really good thing to do before.
Heartworm test yearly. Shouldn't use preventative year-round in most states.
Fecal at least yearly.
Exam to check heart, lungs, gums, abdomen, etc. Very necessary.
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