YorkieTalk.com Forums - Yorkshire Terrier Community - View Single Post - How many shots at one time does your baby get?

Kris Christine · 02-26-2008, 02:10 AM

Recommendations from the American Animal Hospital Association Canine Task Force and other experts indicates that giving individual vaccinations separated by about 2-3 weeks reduces the risk of adverse reactions and reduces the likelihood that multi-valent vaccines will interfere with the immune response, neutralizing or negating the immunological response (see below).

On Page 16 of the 2003 AAHA Guidelines under Immunological Factors Determining Vaccine Safety, it states that: "Although increasing the number of components in a vaccine may be more convenient for the practitioner or owner, the likeli-hood for adverse effects may increase. Also, interference can occur among the components. Care must be taken not to administer a product containing too many vaccines simultaneously if adverse events are to be avoided and opti-mal immune responses are sought. "

Also, a puppy's age is very important when considering vaccination, as the maternal antibodies interfere with the immune response under the age of 16 weeks -- see below.

On Page 16 of the of the American Animal Hospital Association's 2003 Canine Vaccine Guidelines, it reports that: When vaccinating an animal, the age of the animal, the animal's immune status, and interference by maternal antibodies in the development of immunity must be considered. Research has demonstrated that the presence of passively acquired maternal antibodies significantly interferes with the immune response to many canine vaccines, including CPV [parvo], CDV [distemper], CAV-2 [hepatitis] and rabies vaccines."

They further state on Page 17 that: "Multiple vaccinations with MLV vaccines are required at various ages only to ensure that one dose of the vaccine reaches the puppy's immune system without interference from passively acquired antibody. Two or more doses of killed vaccines (except rabies) and vectored vaccines are often required to induce an immune response, and both doses should be given at a time when the passively acquired antibody can no longer interfere. Thus, when puppies are first vaccinated at 16 weeks (or more) of age (an age when passively acquired antibodies generally don't cause interference), one does of an MLV vaccine, or two doses of a killed vaccine, are adequate to stimulate an immune response."

The AAHA Canine Vaccine Guidelines also declare on Page 17 that: "If a pup fails to respond, primarily due to interference by passively acquired maternal antibody, it is necessary to revaccinate at a later time to ensure adequate immunity."

On Page 13 of the 2006 American Animal Hospital Association's Canine Vaccine Guidelines, it lists as the most common reason for vaccination failure is "the puppy has a sufficient amount of passively acquired maternal antibody (PAMA) to block the vaccine......" They elaborate by reporting that at the ages of 14 to 16 weeks of age, "PAMA should be at a level that will not block active immunization in most puppies (>95%) when a reliable product is used."

Duration of Immunity to Canine Vaccines: What We Know and Don't Know, Dr. Ronald Schultz http://www.cedarbayvet.com/duration_of_immunity.htm

The 2003 American Animal Hospital Association's Canine Vaccine Guidelines are accessible online at http://www.leerburg.com/special_report.htm .

The 2006 American Animal Hospital Association's Canine Vaccine Guidelines are downloadable in PDF format at http://www.aahanet.org/PublicDocumen...s06Revised.pdf .

Veterinarian, Dr. Robert Rogers,has an excellent presentation on veterinary vaccines at http://www.newvaccinationprotocols.com/.

02-26-2008, 02:10 AM	#17
Kris Christine YT Addict Join Date: Jan 2008 Location: THE RABIES CHALLENGE FUND Posts: 434	Separating Shots, Puppy Age Recommendations from the American Animal Hospital Association Canine Task Force and other experts indicates that giving individual vaccinations separated by about 2-3 weeks reduces the risk of adverse reactions and reduces the likelihood that multi-valent vaccines will interfere with the immune response, neutralizing or negating the immunological response (see below). On Page 16 of the 2003 AAHA Guidelines under Immunological Factors Determining Vaccine Safety, it states that: "Although increasing the number of components in a vaccine may be more convenient for the practitioner or owner, the likeli-hood for adverse effects may increase. Also, interference can occur among the components. Care must be taken not to administer a product containing too many vaccines simultaneously if adverse events are to be avoided and opti-mal immune responses are sought. " Also, a puppy's age is very important when considering vaccination, as the maternal antibodies interfere with the immune response under the age of 16 weeks -- see below. On Page 16 of the of the American Animal Hospital Association's 2003 Canine Vaccine Guidelines, it reports that: When vaccinating an animal, the age of the animal, the animal's immune status, and interference by maternal antibodies in the development of immunity must be considered. Research has demonstrated that the presence of passively acquired maternal antibodies significantly interferes with the immune response to many canine vaccines, including CPV [parvo], CDV [distemper], CAV-2 [hepatitis] and rabies vaccines." They further state on Page 17 that: "Multiple vaccinations with MLV vaccines are required at various ages only to ensure that one dose of the vaccine reaches the puppy's immune system without interference from passively acquired antibody. Two or more doses of killed vaccines (except rabies) and vectored vaccines are often required to induce an immune response, and both doses should be given at a time when the passively acquired antibody can no longer interfere. Thus, when puppies are first vaccinated at 16 weeks (or more) of age (an age when passively acquired antibodies generally don't cause interference), one does of an MLV vaccine, or two doses of a killed vaccine, are adequate to stimulate an immune response." The AAHA Canine Vaccine Guidelines also declare on Page 17 that: *"If a pup fails to respond, primarily due to interference by passively acquired maternal antibody, it is necessary to revaccinate at a later time to ensure adequate immunity."* On Page 13 of the 2006 American Animal Hospital Association's Canine Vaccine Guidelines, it lists as the most common reason for vaccination failure is "the puppy has a sufficient amount of passively acquired maternal antibody (PAMA) to block the vaccine......" They elaborate by reporting that at the ages of 14 to 16 weeks of age, "*PAMA should be at a level that will not block active immunization in most puppies (>95%) when a reliable product is used."* Duration of Immunity to Canine Vaccines: What We Know and Don't Know, Dr. Ronald Schultz http://www.cedarbayvet.com/duration_of_immunity.htm The 2003 American Animal Hospital Association's Canine Vaccine Guidelines are accessible online at http://www.leerburg.com/special_report.htm . The 2006 American Animal Hospital Association's Canine Vaccine Guidelines are downloadable in PDF format at http://www.aahanet.org/PublicDocumen...s06Revised.pdf . Veterinarian, Dr. Robert Rogers,has an excellent presentation on veterinary vaccines at http://www.newvaccinationprotocols.com/.