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05-26-2015, 02:09 PM | #1 |
YorkieTalk Newbie! Join Date: May 2015 Location: Grantville, Pa
Posts: 1
| Lacey girl with Newly dx PLE my yorkie has recently been dx with ple !! Help !! She now has chronic diarrhea again . She is on prednisone and leukeran. |
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05-26-2015, 02:35 PM | #2 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,447
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In the meantime, what is the vet telling you? Is she eating well? What food is she on?
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05-27-2015, 08:27 AM | #3 |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
Posts: 3,648
| For what it's worth, from what I've read, the prednisone and leukeran treatment is the best that's currently available for PLE. Please keep in close contact with your vet, and keep us posted on how she is doing! |
05-27-2015, 03:08 PM | #5 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,447
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Intestinal Lymphangiectasia I have two pups with it. It is common in yorkies. I also have one with PLE which is a protein losing nephropathy which is related to the kidneys. One of my pups has a thread here from when she was diagnosed. The other one, Rookie, I didn't start a thread about. Here is Cookie's thread: http://www.yorkietalk.com/forums/sic...ia-update.html
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05-27-2015, 03:13 PM | #6 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,447
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What is also very, very important for these pups is a low fat diet. I opted to home cook for Cookie and she is on the same diet. Initially the specialist told me she would be on prednisone for the rest of her life (low dose if her protein levels were good)...but he finally opted to take her off of it since her protein levels improved and so far have remained normal. She was diagnosed in Dec 2011.
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05-27-2015, 03:20 PM | #7 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,447
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There was a recent study that was positive...I am sure that you already know that Phil. LOL
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05-28-2015, 04:54 AM | #8 | |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
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Comparison of a chlorambucil-prednisolone combination with an azathioprine-prednisolone combination for treatment of chronic enteropathy with concurrent protein-losing enteropathy in dogs: 27 cases (2007–2010) The survival rate for prednisone + chlorambucil (leukeran) was much greater than that for prednisone + azathioprine, based on a small study. It is still a very scary disease. | |
05-28-2015, 06:29 AM | #9 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
Posts: 27,447
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As mentioned above, I do believe diet is key in controlling them.
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05-28-2015, 08:01 AM | #10 | |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
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Food Hypersensitivity Reactions in Soft Coated Wheaten Terriers with Protein-Losing Enteropathy or Protein-Losing Nephropathy or Both: Gastroscopic Food Sensitivity Testing, Dietary Provocation, and Fecal Immunoglobulin E - Vaden - 2008 - Journal of To summarize, five out of six dogs with PLE had food sensitivities. Diets containing food items that elicited food sensitivity also worsened the PLE symptoms. The researchers were not able to determine cause and effect, but the two are definitely associated. This kind of ties in with the thread on the Nutriscan test for food sensitivities in dogs. I'm still waiting to hear back from veterinary experts to see if it is a legitimate test for food sensitivities. I HOPE that it is, because if food sensitivities turn out to be a cause of PLE, and if the Nutriscan test really works, then a lot of pain and suffering could be prevented. Right now, I'm keeping an open mind and waiting for more evidence. | |
05-28-2015, 08:06 AM | #11 | |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
Posts: 3,648
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"Food hypersensitivity reactions cause enteritis of varying severity, including PLE, in humans and dogs." That looks like a smoking gun to me. | |
05-28-2015, 08:11 AM | #12 | |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
Posts: 3,648
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"Owners of Soft Coated Wheaton Terriers claim that oftemtimes affected dogs must be fed elimination diets to avoid or reduce clinical signs. In some cases complete resolution of clinical manifestations of the disease follows dietary changes." | |
05-28-2015, 10:12 AM | #13 |
YT 3000 Club Member Join Date: Apr 2013 Location: Urbana, IL USA
Posts: 3,648
| Another article on PLE in dogs... Here is a technical article on PLE in dogs that should be accessible to everyone: http://www.wvc.org/images/session_no.../2013_S17A.pdf It describes the diagnosis, causes, and treatment of PLE in dogs. Apparently, there are three major types of PLE: (1) Intestinal Lymphangiectasia, which is a common form of PLE found in Yorkies. (2) Inflammatory Bowel Disease, which is the most common form found in Wheaten Terriers. (3) Crypt disease. Other causes of PLE are alimentary lymphoma and fungal infections (histoplasmosis). Treatment of PLE includes modifying the diet and using medicines to control the underlying inflammation. Here is an excerpt from the article about dietary changes: "Diet: Dogs with PLE are in a catabolic state, and adequate nutrition is essential. There are currently no published studies critically evaluating nutritional aspects of canine PLE. However, a large body of clinical experience is available. In dogs with primary idiopathic IL, dietary modification centers on feeding a highly digestible diet with low to very low fat content (10-15% on a dry matter basis) to prevent further dilation and rupture of lacteals. Additionally, the diet should contain highly bioavailable dietary proteins and be low in crude fiber. While drug therapy may be administered for a few months (see below) and then discontinued in some cases, dietary therapy should probably be maintained for the length of the dog’s life. In dogs with PLE associated to underlying IBD, many veterinary gastroenterologists report good success with exclusive feeding of a diet consisting of hydrolyzed proteins. Novel protein diets are an alternative approach. Acceptance of the diet is a critical issue in PLE dogs, particularly in the most severely affected animals, which may be anorexic. For each patient, the veterinary care team needs to identify the most palatable diet. Initially, it might be more important to feed a less optimal diet that the dog will be interested in eating, and progressively transition to a more desirable diet." |
05-28-2015, 11:16 AM | #14 | |
Resident Yorkie Nut Donating YT 20K Club Member Join Date: Sep 2006 Location: Texas
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06-02-2015, 11:20 AM | #15 |
YorkieTalk Newbie! Join Date: Dec 2014 Location: Fairfax, Vermont , USA
Posts: 7
| Ple Abby is not responding well to Prednisone and Atopica. Making her food now. The disease and prednisone is really wasting her muscles. I am still trying to make her well. Has anyone ever tried Reiki on a sick dog? |
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